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1.
Rev. Soc. Bras. Med. Trop ; 51(2): 207-211, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-1041456

ABSTRACT

Abstract INTRODUCTION: Human T-cell lymphotropic virus type 1 (HTLV-1)induces exaggerated Th1 responses, whereas atopy is associated with exacerbated Th2 responses. METHODS: Here, a cross-sectional study compared the prevalence of atopy in HTLV-1 carriers and HAM/TSP patients. It also compared the spontaneous cytokine production in HTLV-1-infected individuals. A retrospective cohort study evaluated the development of neurological manifestations in atopic and non-atopic carriers. RESULTS: Atopic HAM/TSP patients with high IFN-γ production exhibited higher IL-5 levels than non-atopic patients. Allergic rhinitis accelerated the development of Babinski signals and overactive bladders. CONCLUSIONS: Abnormal Th1 and Th2 responses coexist in HTLV-1-infected individuals and allergic diseases may worsen the clinical course of HTLV-1 infections.


Subject(s)
Humans , Male , Female , HTLV-I Infections/complications , Hypersensitivity, Immediate/epidemiology , Nervous System Diseases/virology , HTLV-I Infections/immunology , HTLV-I Infections/pathology , Paraparesis, Tropical Spastic/complications , Paraparesis, Tropical Spastic/immunology , Paraparesis, Tropical Spastic/pathology , Cross-Sectional Studies , Retrospective Studies , Cohort Studies , Cytokines/biosynthesis , Hypersensitivity, Immediate/immunology , Hypersensitivity, Immediate/blood , Middle Aged , Nervous System Diseases/immunology
2.
Int. arch. otorhinolaryngol. (Impr.) ; 19(1): 96-98, Jan-Mar/2015. graf
Article in English | LILACS | ID: lil-741540

ABSTRACT

Introduction Mucoceles are benign expansive cystic formations, composed of a mucus-secreting epithelium (respiratory or pseudostratified epithelium). Nasolacrimal mucocele occurs in a small proportion of children with nasolacrimal duct obstruction and is characterized by a cystic mass in the medial canthus with dilation of the nasolacrimal duct; although dacryocystoceles are rare in adults, they have been reported in patients with trachoma. Objective Discuss clinical aspects, diagnosis, and therapeutic management of mucocele of nasolacrimal duct based on literature review. Resumed Report The authors report a case of bilateral congenital nasolacrimal duct cysts in a 30-year-old man, identified as a tumor in the topography of both lacrimal sacs since birth without associated symptoms. The patient underwent successive surgical treatments, leading to recurrence of the tumor at the right side and recurrent local infections. Conclusion Endoscopic dacryocystorhinostomy has been increasingly used with good results and success rates similar to the external access. .


Subject(s)
Animals , Humans , Genetic Predisposition to Disease/genetics , Mutation/genetics , Nervous System Diseases/genetics , Sodium-Potassium-Exchanging ATPase/genetics , Databases, Bibliographic/statistics & numerical data , Hemiplegia/genetics , Models, Molecular , Nervous System Diseases/diagnosis , Parkinson Disease/genetics , Sodium-Potassium-Exchanging ATPase/metabolism
3.
Arq. int. otorrinolaringol. (Impr.) ; 16(1): 130-134, fev.-mar. 2012. ilus
Article in English, Portuguese | LILACS | ID: lil-620563

ABSTRACT

INTRODUÇÃO: A osteomielite frontal é uma complicação de rinossinusite que pode ter evolução aguda ou crônica. Há reação inflamatória com aumento da pressão intra-óssea, isquemia e necrose local, levando à formação de abscesso ósseo. Não havendo drenagem, ocorrerá descolamento do periósteo, invasão de partes moles e piora da isquemia com posterior sequestro ósseo. MÉTODO: Relato de caso de um paciente internado em serviço de emergência de outra instituição por complicação de rinossinusite que foi encaminhado para o Serviço de Otorrinolaringologia do Hospital Universitário Professor Edgard Santos da Universidade Federal da Bahia. RELATO DE CASO: Paciente masculino, 16 anos, apresentou-se ao serviço de emergência de outra instituição com cefaleia, vômitos e febre que evoluiu com edema periorbitário e frontal à esquerda, cursando com flutuação palpebral e frontal.Submetido à drenagem de abscesso palpebral e frontal, com antibioticoterapia de amplo espectro sem melhora. Encaminhado para o nosso serviço mantendo edema e flutuação em região frontal e edema leve em região periorbitária esquerda. A endoscopia nasal evidenciou edema em meato médio à esquerda e a tomografia computadorizada mostrou sinusite fronto-etmoidal à esquerda e sinais de osteomielite frontal com sequestro ósseo e empiema epidural.Submetido à cirurgia endoscópica nasossinusal, acesso externo para exérese do osso frontal acometido e drenagem do empiema epidural. Evoluiu com remissão da doença. CONSIDERAÇÕES FINAIS: A falência no diagnóstico e no tratamento das complicações da rinossinusite pode levar a sequelas e complicações fatais.O diagnóstico de osteomielite frontal é firmado pela suspeita clinica e confirmado por exames radiológicos.A cirurgia está indicada quando a evolução for insidiosa, havendo sequestro ósseo ou complicações intracranianas.


INTRODUCTION: The frontal osteomyelitis is a complication of rhinosinusitis which can evolve to acute or chronicle. There is inflammatory reaction by the increasing of intraosseous pressure, ischemia and local necrosis, leading to bone abscess formation. There is no drainage, it will occur detachment of the periosteum, soft tissue invasion and worsening of ischemia with subsequent bone sequestration. METHOD: Case report of an inpatient in an emergency service of another institution by the complication of rhinosinusitis who was referred to the Otorhinolaryngology Service of University Hospital Professor Edgard Santos of Federal University of Bahia. CASE REPORT: Male patient, 16 years-old, presented himself to the ER of another institution with cephalea, vomits and fever which evolved to periorbital edema and frontal to the left, moving to palpebral fluctuation and frontal. Subjected to frontal and palpebral abscess drainage, with broad-spectrum antibiotic therapy with no improvement. He was referred to our service keeping edema and fluctuation in region frontal and light edema in left periorbital region. The nasal endoscopy showed edema in meatus to the left and the computerized tomography showed fronto-ethmoid sinusitis to the left and signs of frontal osteomyelitis with bone sequestration and epidural empyema. Subjected to sinasal endoscopy surgery, external Access or removal of the frontal one affected and epidural empyema drainage. Evolved to the remission of the disease. FINAL CONSIDERATIONS: Failure in the diagnosis and rhinosinusitis complication treatment can lead to sequalae and fatal complications. The diagnosis of the frontal osteomyelitis is confirmed by the clinical suspicion and confirmed by radiological examination. The surgery is indicated when the evolution is insidious, there is bone sequestration and intracranial complications.


Subject(s)
Humans , Male , Adolescent , Abscess/surgery , Abscess/microbiology , Clinical Evolution , Drainage , Frontal Bone/physiopathology , Frontal Bone/pathology , Osteomyelitis/complications , Frontal Sinusitis/surgery , Frontal Sinusitis/complications , Frontal Sinusitis/microbiology , Magnetic Resonance Imaging , Tomography, X-Ray Computed
4.
Arq. int. otorrinolaringol. (Impr.) ; 15(2): 241-244, abr.-jun. 2011. ilus
Article in English, Portuguese | LILACS | ID: lil-594672

ABSTRACT

Introdução: Dentre as complicações da rinossinusite, as orbitárias são as mais frequentes, e estas, ocorrem na maioria dos casos entre jovens e crianças. Complicações simultâneas envolvendo a órbita e o espaço intracraniano são extremamente raras, mas devem ser tratadas agressivamente pois oferecem alta taxa de morbidade e mortalidade. Relato do Caso: Neste trabalho, os autores relatam um caso de um paciente que se apresentou com celulite pré-septal e abscesso epidural, como complicações simultâneas de uma rinossinusite aguda. No paciente deste estudo, optou-se pelo tratamento clínico associado à cirurgia endoscópica nasossinusal e drenagem neurocirúrgica do abscesso intracraniano. A TC foi suficiente no caso apresentado para a realização do diagnóstico. Comentários Finais: Recomenda-se entretanto, que nos casos de pacientes com complicações da rinossinusite, a investigação da extensão intracraniana seja aprofundada, mesmo quando esta, a princípio não seja tão evidente. Dada a natureza polimicrobiana dessas infecções, uma antibioticoterapia agressiva guiada por cultura e um acompanhamento por equipe multidisciplinar, aumentam consideravelmente as chances de sucesso.


Introduction: Among the rhinosinusitis complications, the orbital are the most frequent ones, occurring mostly in the youngsters and children. Simultaneous complications involving the intracranial orbit and space are extremely rare, but they must be severely treated for they have a high rate of morbidity and mortality. Case report: In this work, the authors report a case of a patient who appeared to have preseptal cellulites and epidural abscess, in the form of simultaneous complications of an acute rhinosinusitis. In the patient of this case, choice was made for a clinic treatment associated with a nasosinusal endoscopic surgery and neurosurgical drainage of the intracranial abscess. CT was enough to achieve the diagnosis of this case. Final commentaries: However, it is recommended that, in cases where patients have rhinosinusitis complications, an extensive intracranial investigation needs to be deepened even when this is not so evident in the beginning. Given the polymicrobial nature of these infections, an aggressive culture-guided antibiotic therapy and a multidisciplinary follow-up significantly increase the likelihood of success.


Subject(s)
Humans , Male , Adolescent , Epidural Abscess/pathology , Rhinitis/complications , Sinusitis/complications , Orbit/physiopathology
5.
Arq. int. otorrinolaringol. (Impr.) ; 14(3)jul.-set. 2010. tab, graf
Article in Portuguese, English | LILACS | ID: lil-558352

ABSTRACT

Introdução: Papiloma nasossinusal é um tumor benigno com origem no epitélio schneideriano da parede nasal lateral. Sua incidência é rara e de acordo com a literatura responde por 0,5 a 4% de todos os tumores nasais. Objetivo: Reportar a experiência da nossa instituição no tratamento do papiloma nasossinusal invertido utilizando acesso endoscópico e comparar os resultados obtidos com os relatos da literatura. Método: Estudo retrospectivo de todos os pacientes com papiloma nasossinusal que realizaram tratamento cirúrgico puramente endoscópico no ambulatório de Otorrinolaringologia do Hospital das Clínicas da Universidade Federal da Bahia (UFBA), no período de janeiro de 2004 a maio de 2010. Resultados: Um total de 12 pacientes foi incluído neste estudo. O seguimento médio foi de 23 meses. Houve 1 caso de recidiva. Não ocorreu transformação maligna nestes casos. Conclusão: O tratamento do papiloma nasossinusal tem sido amplamente beneficiado com o avanço das técnicas endoscópicas, com taxas de recorrência equivalentes àquelas reportadas por acesso externo. Exames de imagem são fundamentais no planejamento pré-operatório e na decisão da técnica cirúrgica. Um seguimento regular e de longo prazo é essencial para um bom acompanhamento da evolução desta patologia.


Introduction: Sinonasal Papilloma is a benign tumor originating from the epithelium schneiderian lateral nasal wall. Its incidence is rare and according to literature accounts for 0.5 to 4% of all nasal tumors. Objective: To report our institution's experience in the treatment of sinonasal inverted papilloma using endoscopic approach and compare the results with the literature. Methods: A retrospective study of all patients with sinonasal papillomas who underwent a purely endoscopic surgery in the Otorhinolaryngology, Hospital das Clinicas, Federal University of Bahia (UFBA), from January 2004 to May 2010. Results: A total of 12 patients were included in this study. The median follow-up was 23 months. There was one case of recurrence. Malignant transformation has not occurred in these cases. Conclusion: The treatment of sinonasal papilloma has been largely benefited from the advances in endoscopic techniques, with recurrence rates equivalent to those reported for external access. Imaging exams are essential in preoperative planning and the decision of surgical technique. A regular follow-up and long term is essential for a good monitoring of the evolution of this pathology.


Subject(s)
Paranasal Sinus Diseases/surgery , Endoscopy , Otorhinolaryngologic Surgical Procedures , Papilloma, Inverted/surgery , Paranasal Sinuses/surgery
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